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COVID 19 Updates from RheumNow

The Overpricing of Drugs (1.14.2022)

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com. This week we discuss amputations, a $57 billion RA market, an FDA approved drug for Cat arthritis and drug that works in Sjogren's.

Hold Myophenolate or Not with COVID-19 Vaccination?

While the American College of Rheumatology (ACR) recommends holding mycophenolate (MMF) in rheumatic and musculoskeletal diseases (RMD) patients receiving COVID-19 vaccines, there is limited data on such an approach.

COVAX Registry: Safety of COVID-19 Vaccines in Rheum Patients

The EULAR Coronavirus Vaccine (COVAX) physician-reported registry has shown that the use of COVID-19 vaccines in people with inflammatory/autoimmune rheumatic and musculoskeletal disease (I-RMD) is effective, safe, and well tolerated.

COVID-19 in Pregnant Rheumatic Women

The Global Rheumatology Alliance (GRA) has studied the outcomes of women with rheumatic disease who were pregnant at the time of infection with coronavirus disease 2019 (COVID-19).

2021 Rheumatology Year in Review

“One faces the future with one’s past” – Pearl S. Buck

2021 was the year we waited for the other shoe to drop; with the pandemic stone in your shoe, you waited for:

Comorbidities Drive Risk of Severe Outcomes with COVID-19

The current edition of the MMWR from the CDC shows that among those vaccinated against COVID-19, there is a low risk of severe outcomes (hospitalization and death); the highest risk is seen in those with multiple comorbidities.

COVID Breakthrough Infections with Arthritis and HIV

MedPage Today

Among immunocompromised individuals vaccinated against COVID-19, solid organ transplant recipients as well as those with HIV and rheumatoid arthritis (RA) were significantly more likely to experience breakthrough infections versus people without immune dysfunction, a retrospective study found.

New Onset Rheumatic Disorders with COVID-19 Infection

The journal Cells has published a review of new rheumatic disorders following COVID-19 infection. Rheumatologists have infrequently noted such events and wondered what is the true incidence or range of possible manifestations.

Clinical Practice Guidelines for Multisystem Inflammatory Syndrome in Children

Multisystem inflammatory syndrome in children (MIS-C) is new and serious complication of COVID-19 that preferentially affects adolescents. A review of proposed management guidelines is compiled in this report, suggesting a unified approach to therapeutic management of MIS-C.

Safety of COVID-19 Vaccines in Rheumatic Patients

Since the introduction of COVID-19 vaccines in January 2021, rheumatologists have fully advocated the protective benefits of their use - yet many have rarely noted flares and reactive side effects worrisome to patients.  Now a multinational study shows that the use of COVID vaccination in rheumat

Best of 2021: Jack of All Subspecialties

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com

Social

Patients on biologics are NOT at higher risk for COVID-19 infx. Retrospective matched cohort study compared 7631 Biologic Rx pts to 74910 matched cohort with equal Infx & death rates. COVID infx assoc w/ age, minorities, more comorbidities https://t.co/GxmgWIbgSo

Dr. John Cush @RheumNow ( View Tweet )

5 days 5 hours ago
ICYMI: Comorbidities Drive Risk of Severe Outcomes with COVID-19https://t.co/9GgfvgnMke https://t.co/JGHp0mVPpF
Dr. John Cush @RheumNow ( View Tweet )
6 days 7 hours ago
ICYMI: New Onset Rheumatic Disorders with COVID-19 Infection The journal Cells has published a review of new rheumatic disorders following COVID-19 infection. Read more: https://t.co/X2DLznJynL https://t.co/wLCWt7gwgf
Dr. John Cush @RheumNow ( View Tweet )
1 week 1 day ago
@ACRheum guidance from 2/2021 recc holding HCQ in pts with #COVID19. Are you doing this? We need updated guidances with #Omicron @rheum_cat @LCalabreseDO @CCalabreseDO @RADoctor @RheumNow @JYazdanyMD

TheDaoIndex @KDAO2011 ( View Tweet )

1 week 4 days ago
There have been reports of COVID-19 vaccination causing adult-onset Still’s dz onset. Now a case of AOSD, given the BNT162b2 vax and developing Macrophage activation syndrome w/ ferritin levels of 136,680 µg/l https://t.co/caKef9BGDR

Dr. John Cush @RheumNow ( View Tweet )

1 week 4 days ago
Safety of COVID-19 Vaccines in Rheumatic Patients A multinational study shows that the use of COVID vaccination in rheumatic and musculoskeletal disease (I-RMD) is safe, well-tolerated with very rare serious adverse events (AEs).https://t.co/d30zbfa0f8 https://t.co/OM6GzAzTvQ
Dr. John Cush @RheumNow ( View Tweet )
1 week 5 days ago
Does COVID Vax reduce adolescent MIS-C risk? In France 77% of teens recv COVID Vaccine by 10/2021. From Sept-Oct 2021,107 MIS-C kids were hospitalized in France; 31% were eligible but not vaccinated. MIS-C risk dropped 91% (0.09) after 1st first vax dose https://t.co/mF0L2VnEoi https://t.co/R33n1FCN3X
Dr. John Cush @RheumNow ( View Tweet )
1 week 5 days ago
Best of 2021: Israel provides COVID vaccine answers for rheumatic disease patientshttps://t.co/3mWEjdAnLL https://t.co/It5VjbQMoI
Dr. John Cush @RheumNow ( View Tweet )
2 weeks 4 days ago
We're now learning about the T-cell response to Omicron after an mRNA vaccine boosters. That's why these new findings in people with multiple sclerosis on immunosuppressive therapy are very encouraginghttps://t.co/Gzv9sQTsuA https://t.co/SoezeVWgR3
Eric Topol @EricTopol ( View Tweet )
3 weeks 5 days ago
listen to my take on how out pt mgmnt for #immunocompromised pts can be optimized & how we MUST protect them fr #COVID19 @VuMedi linkhttps://bit.ly/3FfdYGB@RheumNow @NatalieEAzarMD @BolekBerqui @KDAO2011 @rhjeumn @CreakyJoints @AWIRGROUP @RNSociety @RheumAPP https://t.co/hKVIg8Aw2g
Leonard Calabrese @LCalabreseDO ( View Tweet )
3 weeks 5 days ago
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