Geriatric Rheumatology:Improving care of aging patients Dr.Kathryn Dao ( @KDAO2011) moderates a panel w/ Drs.Una Makris, Katherine Wysham, Sebastian Sattui + Devyani Misra, as they discuss aspects of improving care of/outcomes for aging patients. #ACR21 https://t.co/lF3yUZBEkd https://t.co/hYufA8ptqj

Targeting the HUGE dilemma!🎯 #Psoriatic vs Erosive #OA PsA 👉 Fluffy bone formation(enthesitis of phalanges) 👉 Marginal erosions(vs central) 👉 Many jts in same digit(ray inv) 👉 Periarticular SOFT tissue swelling (dactylitis). 👉 NOT much hand OA #ACR21 RadiologyBootCamp https://t.co/OQLPoeRLny

Live from #ACR21: Learning about osteoarthritis from Dr. Marc Hochberg. "Don't use the term degenerative joint disease." -much more involved. I like this figure of the multiple different phenotypes. #ACRAmbassador https://t.co/UwU4vCmYXa

OA oral session - abstract 1904 Devin Driscoll (mentor @tuhina_neogi) presenting data from MOST: Evaluation of Neuropathic-like Symptoms and Objective Signs of Neuropathy Post-Knee Replacement #ACR21 https://t.co/APZAJdHH5M

Quick plug: not all joint pain in ICI-treated pts needs reflex steroids eg OA can get exacerbated by ICI Rx (ICI-aOA) call rheum, hold the PNL & save tumor response @ReidMDMPH @got_rheum @lovetolearn27 +me #ACR21 ABST1518 @RheumNow our paper @jitcancer https://t.co/InespbOn6m https://t.co/HSjtGrwePE

CBD for pain in hand OA/inactive PsA: - works in animal models (many things do) - other neg RCTs didn't use CBD itself - DBRCT: 12w continuous, n=136, min dropout Result: does absolutely nothing I bet big money it will be tried again & again @Joner_MD #ACR21 ABST1456 @RheumNow https://t.co/lZLVrgrKST

If you need a #knee replacement move out of Ontario. More income disparity of access to #TKR in Ontario vs Pennsylvania. Lack of universal #healthcare in 🇨🇦. Oh Canada we fail. @RheumNow #ACR21 abst#1037 https://t.co/kobUlT3Ugr

Oral Calcitonin not recommended for OA - studies did not show efficacy Strontium Ranelate study below was considered a positive study in KOA with efficacy but had Cardiovascular toxicity - now off the market. https://t.co/gcYH9xoxeo

Cathepsin K - has some promise in Knee OA - now going to Phase 3 @RheumNow https://t.co/exUFqcCJy1

Marc Hochberg lecture at #ACR21 - Bisphosphonates limited and inconclusive data in radiographic progression of OA, some ⬇️ in bone marrow lesions! @RheumNow https://t.co/ciMUINBLwm

Dr. Marc Hochberg delivering the Oscar Gluck Memorial lecture - His talk titled "The Role of Bone in OA". He begins with this statement.... "DJD... Should never be used" - the rest of the lecture explains why. #ACR21 https://t.co/lYGsFu4Wpr https://t.co/IWP5J73mFO

MCP, wrist, elbow, shoulder and ankle: Not common sites for #osteoarthritis so consider a metabolic disease like CPPD🧐 @RheumNow #ACR21 #RheumTwitter #MedTwitter https://t.co/utId4ljsZK

Phase 3 observational extension study of Lorecivivint, intra-articular CLK/DYRK inhibitor that modulates Wnt and inflammatory pathways. Safety and tolerability. Efficacy at 6 and 12 month, but at 18month it disappeared @RheumNow #ACR21 abst#0729 https://t.co/9ycbVGKkmy

Single Intraarticular Canakinumab in Knee OA - 18-week randomized, double-blind, double-dummy Placebo and naproxen-controlled - effect no different than Placebo. Some efficacy in subgroup with high hsCRP. Need for subtypes in OA @rheumnow #ACR21 #abst0728 https://t.co/YlKTMf56wF

answer: CPPD. 👉CPPD can look like OA but can be more aggressive. 👉Look for chondrocalcinosis at the triangular ligament, pubic symphyis, superiolateral femoral head 👉A common cause of scapholunate widening 👉CPPD loves the patellofemoral joint (knee joint may be spared) https://t.co/wgYjJwYvb0

Wanted to highlight our work @HSpecialSurgery presented at #ACR21 using unsupervised clustering of multimodal data - histology and ultrasound to identify phenotypes such as moderately inflammatory subtype in #osteoarthritis @RheumNow #abst0212 some features highlighted in fig https://t.co/HRzhMXctB9

STEP-KOA trial: a promising intervention for knee #osteoarthritis?🤔 @RheumNow #ACR21 #YearinReview https://t.co/6Vkx0WR0tx

#ACR21 Year in Review: Stepped Exercise program for knee OA - decrease in pain and increase in function, without objective measures showing improvement. Time to prescribe exercise! @Rheumnow https://t.co/LrNZ3pBO9i