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morbidity,covid,heart,lung,brain

Multimorbidity Burden in Rheumatoid Arthritis

May 17, 2022

Crowson and colleagues at the Mayo Clinic have shown that rheumatoid arthritis (RA) patients have a higher prevalence of multimorbidity with as many as 44 different morbidities of interest in RA.



This population-based study examined prevalent RA as of January 2015 and sought to

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Our response to statins is influenced by our gut microbiome https://t.co/xKZdxO13va New @MedCellPress https://t.co/BxwhRhMAX9
Eric Topol @EricTopol( View Tweet )
May 11, 2022
Gout pills injection

Allopurinol Use Does Not Increase Mortality in Gout with Chronic Kidney Disease

May 03, 2022

A population based trial has shown that allopurinol use dose escalation and achieving target uric acid levels (with allopurinol), was not associated with increased mortality in patients with gout and concurrent CKD



To examine the relation of allopurinol initiation, allopurinol dose

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$30 Billion and Counting (4.29.2022)

Apr 29, 2022

Dr. Jack Cush reviews the news and journal reports and takes viewer questions this week.

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Cardiovascular risk (CVR) was assessed in Psoriasis (#PSO) & #PSA in multiracial population in S Brazil using the Framingham Risk Score. Compared to controls PSO & PSA had higher FRS (16.3 & 18 vs 10.6) and also increased with age. highttps://bit.ly/3k7ySi8

Dr. John Cush @RheumNow( View Tweet )

Apr 26, 2022
Liver,hepatic,red

Arthritis Predicts Hepatic Fibrosis in Hemochromatosis

Apr 25, 2022

Mayo Clinic Proceedings reports the results of a retrospective, cross-sectional of patients with HFE hemochromatosis showing that advanced hepatic fibrosis is primarily seen in those with arthritis due to HFE hemochromatosis. 



A total of 112 patients with a liver biopsy confirmed

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TNR,controversies,psa

TNR - Controversies in PsA

Apr 20, 2022

Held on April 19, 2022, Tuesday Night Rheumatology: Controversies in PsA, featured a lively and informative panel discussion, moderated by Dr. Jack Cush.



The PsA Expert panelists included:



  • Dr. Dafna Gladman, Toronton

  • Dr. Joseph Merola, Boston

  • Dr. Peter
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Male vs. Female Responders (4.15.2022)

Apr 15, 2022

Dr. Jack Cush reviews the news and journal Reports from the past week on RheumNow.com - including fellowship COVID-19 concerns, the limits of T2T in gout and the real odds of RA remission with your first biologic. 




  1. Downward Effects! Real world data from 22,934 UK #RA pts

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RheumNow Podcast – What You Do For & What You Do To the Patient (4.8.2022)

Apr 08, 2022

Dr. Jack Cush reviews the news and journal articles from the past week and discusses the use of fibroscan in RA, steroid hip injections in OA and famous quotes from a famous cardiologist.




  1. CorEvitas Registry study of173 Axial #PsA pts showed 6 mos of bDMARD/tsDMARD resulted

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Heart Risks Elevated in RA Patients Despite Biologic Tx Hopes that biologic drugs for RA would cancel the extra cardiovascular risks normally seen with the disease dimmed a little in the face of findings from a population-based study from Scandinavia.https://t.co/qUYG3U2Ind https://t.co/oCpNnDmxIX
Dr. John Cush @RheumNow( View Tweet )
Apr 01, 2022
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PsA All the Way – Unmet Needs

Apr 01, 2022

Throughout the month of April 2022, RheumNow is introducing a new approach to education and information sharing – a campaign devoted to a single disease. Our first campaign is entitled PsA All the Way: RheumNow will escalate awareness on this topic, its unmet needs, clarify advances and discuss

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Heart Risks Elevated in RA Patients Despite Biologic Tx

MedPage Today
Mar 31, 2022

Hopes that biologic drugs for rheumatoid arthritis (RA) would cancel the extra cardiovascular risks normally seen with the disease dimmed a little in the face of findings from a population-based study from Scandinavia.

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Comorbidity Drives Risk of Death in Gout Patients

Mar 24, 2022

A study of men with gout from the US Veteran’s Health Administration (VHA) shows that excess mortality in gout could be attributed to comorbidities.



A matched cohort study done between 1999 - 2015, compared gout and non-gout patients, looking at clinical variables and mortality rates

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hospital,surgery

SLE Higher Risk of Postoperative Cardiac Events

Mar 23, 2022

ACR Open Rheumatology reports that systemic lupus erythematosus (SLE) patients have a higher risk of postoperative major adverse cardiac events (MACE) that can be identified by common cardiac risk measures.

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Having the MUC5B promoter variant increases odds of RA-ILD w/ earlier onset in RA, esp w/ older age of RA onset. Mass Gen Biobank study of 1,005 RA pts; MUC5B found in 15% w/ incr risk of RA-ILD (OR 3.34) & RA onset after 55 yrs (OR 1.52) https://t.co/5odVWnpuxo https://t.co/zeKxADTSBZ
Dr. John Cush @RheumNow( View Tweet )
Mar 23, 2022
Bronchiectasis_342x198_M1200048.jpg

Seropositivity Linked to Bronchiectasis in Rheumatoid Arthritis

Mar 17, 2022

Rheumatoid arthritis associated bronchiectasis (RA-BR) is uncommon, and is unrelated to interstitial lung disease (ILD), but like ILD, can substantially impact RA outcomes.



A case-control study from the Mass General Brigham Biobank compared RA-BR (57 cases) and RA controls without RA-

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ICYMI: Good review of Diagnosis and Treatment of Pulmonary Sarcoidosis in JAMA. - Lung progression (in only 10%) assoc w/ 12-18% 5yr mortality - Sx Sarcoid w/ Lung: start Pred 20 to 40 mg/d for 2 -6 wks - Steroid sparing w/ MTX, AZA or TNFi https://t.co/Ue4V1uAhRF https://t.co/5ap3bPzoNk
Dr. John Cush @RheumNow( View Tweet )
Mar 12, 2022
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RheumNow Live is Coming to Town (3.11.2022)

Mar 11, 2022

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.

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French GAZEL study of 20,625 pts showed a confirmed RA Dx was significantly assoc w/ increased CV risk (HR 3.03; 1.13–8.11) independent of usual CV risk factors. RF or ACPA (+) without RA was not associated with CV events https://t.co/DG8o5d9hHE https://t.co/5n9uDAhSrF
Dr. John Cush @RheumNow( View Tweet )
Mar 04, 2022
ACR Best

2021 Top Articles from Arthritis & Rheumatology

ACR
Mar 02, 2022

The ACR journal, Arthritis & Rheumatology, has publish a listing of top articles in 2021 as measured by Altmetric, an online service that tracks what gets "clicked" and discussed.  Interestingly, this includes 4 guidelines and 5 COVID-related papers. Many of these are included in the

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RheumNow Podcast - RWCS 2022 Roundup (2.19.2022)

Feb 21, 2022

Drs. Jack Cush and Artie Kavanaugh review the highlights of the RWCS (Rheumatology Winter Clinical Symposium) from Maui.


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CV,risk,MI,heart,cardiac

CV Risk Management in Rheumatic Disease Patients

Feb 15, 2022

The European League against Rheumatism (EULAR) has developed recommendations for cardiovascular risk (CVR) management in rheumatic disease patients based on literature review and expert consensus.



These recommendations are applicable to patients with gout, vasculitis, systemic

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Hand OA and Heroes in Rheumatology (2.11.2022)

Feb 11, 2022

Interesting reports this week about dementia, who gets hand OA and a great list of women Heroes and Pillars of Rheumatology. Tune in as Dr. Jack Cush reviews the news and journal articles from this past week in RheumNow.com.

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coronavirus,COVID,MISC,mask

ACR Updates Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With COVID

Feb 09, 2022

A Task Force from the ACR has provided an updated (version 3) guidance for the diagnosis and management of Multisystem Inflammatory Syndrome in Children (MIS-C), a COVID related condition characterized by fever, inflammation, and multiorgan dysfunction. The current guidance also applies to

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An Ounce of Prevention (2.4.2022)

Feb 03, 2022

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com.  He discusses the GI side effects of IL-17 inhibitors, downstream revenues from rheumatology care and dietary prevention of gout. 

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