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Fibromyalgia/Pain

COVID,vaccinate,injection,green

COVAX Registry: Safety of COVID-19 Vaccines in Rheum Patients

Jan 13, 2022

The EULAR Coronavirus Vaccine (COVAX) physician-reported registry has shown that the use of COVID-19 vaccines in people with inflammatory/autoimmune rheumatic and musculoskeletal disease (I-RMD) is effective, safe, and well tolerated.



Rheumatic and autoimmune patients were not

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Duloxetine added to usual analgesics failed to improve pain in 132 hip or knee OA pts by WOMAC pain scores: 1) Dulox + usual care vs 2) Usual care showed no diff in pain at 3 mos or 12 mos. https://t.co/9gR2PNVrPl

Dr. John Cush @RheumNow( View Tweet )

Jan 11, 2022
ASK CUSH ANYTHING! Have a Rheumatology question or case for Jack Cush? Record it here and we may feature it on an upcoming podcast. Tell us your name and where you practice rheumatology.https://t.co/7q5sMQuIHj https://t.co/ksCCvzdxka
Dr. John Cush @RheumNow( View Tweet )
Jan 05, 2022
Registration now open for RheumNow Live! Join us March 19-20 in Irving, TX or virtually!https://t.co/py6Gp8sPh8

Dr. John Cush @RheumNow( View Tweet )

Dec 24, 2021
Download your RheumaKnowledgy Card https://t.co/GauMzCH5lB https://t.co/CrS7r6RAoc

Dr. John Cush @RheumNow( View Tweet )

Dec 22, 2021
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Indications Awaiting (12.17.21)

Dec 17, 2021

There's good news and bad news in rheumatology fellowship matching for 2022.  There's also new FDA approvals and indications, but a new serious safety warning has arisen from the CDC about the J&J COVID-19 vaccine. 

Dr. Jack Cush reviews the latest news, journal reports, regulatory

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Fibromyalgia pts are prone to suicidal ideation (29.6%; OR 9.1), attempts (5.7%; OR 3.1), & events (OR 1.38), but significance lost when correcting for psych illness. Risk assoc w/ work, dz severity, obesity, addiction, chronic pain & co-morbidities. https://t.co/jjiZ5iZBjP https://t.co/cuCsKKcOj7
Dr. John Cush @RheumNow( View Tweet )
Dec 13, 2021
ASK CUSH ANYTHING! Have a Rheumatology question or case for Jack Cush? Record it here and we may feature it on an upcoming podcast. Tell us your name and where you practice rheumatology.https://t.co/tl3Nkxdv0B https://t.co/WwxgWGuVcC
Dr. John Cush @RheumNow( View Tweet )
Dec 10, 2021
nobel-prize-1356450__180.jpg

Pain is the Focus of the 2021 Nobel Prize in Medicine

Dec 08, 2021

The 2021 Nobel Prize in Medicine and Physiology was jointly awarded to Drs. David Julius and Ardem Patapoutian for their discoveries of receptors for temperature and touch. Their work on neural signaling of heat and touch (tactile) relate to many physiologic conditions including chronic pain

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The Last CBD Trial: Dr. David Liew ( @drdavidliew) discusses abstract #1456 presented at the #ACR21 annual meeting.https://t.co/Kw3h2vTJkv https://t.co/WZGV7iOFlA
Dr. John Cush @RheumNow( View Tweet )
Nov 24, 2021
Fibromyalgianess Glucocorticoid Persistence in RA Patients: Dr. Sheila Reyes ( @RHEUMarampa) discusses abstract #0120 presented at the #ACR21 annual meeting.https://t.co/9yOM5rSARv https://t.co/Gq2YxbxkmM
Dr. John Cush @RheumNow( View Tweet )
Nov 09, 2021
Interesting results where cannabidiol NEG results in RCT in hand OA and PsA. ? Throw out the ‘pot’with the dish water? Did it stimulate appetites? Was pain the same but interference less? Abst#1456 #ACR21 @RheumNow https://t.co/rnz82Paxkr
Nov 08, 2021
#ACR21 Ab#1166. How many of your pts use marijuana? ⭐️Probably more than you think! ▶️57% have tried, >50% use at least weekly ▶️67% doctors thought <20% of pts use it 🔥Pts over 40 yo MORE likely to report marijuana use @Rheumnow https://t.co/0uW8rZvf1k https://t.co/ShMnR0faHr
Nov 08, 2021
Telemedicine black computer

Can tender and swollen joint counts work in a telemedicine world?

Nov 08, 2021

In a world where telemedicine and virtual care are not going away, is there value in patients assessing their own tender and swollen joints?



Work from the Canadian Early Arthritis Cohort (CATCH, @earlyarthritis) presented by Dr. Vivian Bykerk (@BykerkVivian) is the subject of two

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Sublingual Cyclobenzaprine for fibromyalgia. It seems to improve pain, and across the board on secondary endpoints. But all by a modest effect. Big placebo response also. Not time to get overly excited yet. Abstr#0477 #ACR21 @RheumNow https://t.co/aUtwaH5oEh
Richard Conway @RichardPAConway( View Tweet )
Nov 06, 2021
@BethIWallace et al. on fibromyalgianess and GC in #rheumatoidarthritis pts. Accdg to their study, pts w/⬆ levels of fibromyalgianess at BL had higher odds of GC persistence on ffup. Something to consider when evaluating need for GC adjustment. @RheumNow #ACR21 abs0120 https://t.co/MTWEXGHJ2n
Nov 06, 2021
Study by @BethIWallace @Tuhina_Neogi shows that we seem to treat fibromyalgia symptoms with steroids in RA patients. Its a bad idea in fibromyalgia, and has got to be bad practice in RA too. Abstr#0120 #ACR21 @RheumNow

Richard Conway @RichardPAConway( View Tweet )

Nov 06, 2021
DNA,genotyping,gene,sequencing

Large GWAS Study Reveals Genetic Basis for Osteoarthritis Phenotypes

Oct 29, 2021

Cell has published the results of a multinational, GWAS meta-analyses of 826,690 individuals that included 177,517 osteoarthritis patients, finding 52 previously unknown osteoarthritis (OA) genetic risk variants and linking OA genetic risks with joint distribution and pain-related

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RheumNow Podcast – Like Father, Like Daughter (10.29.2021)

Oct 29, 2021

Bad things happen when our patients go into the ICU and it's not always due to the disease. Good things happen when we rise from sitting. And guess what? Rheumatologists are setting cardiology straight about hydroxychloroquine and chloroquine. This, and a special recognition of parent-child

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ankle,xray

Platelet-Rich Plasma Injections Fail in Ankle Osteoarthritis

Oct 27, 2021

A controlled trial of intra-articular platelet-rich plasma (PRP) injections into the ankle of osteoarthritis (OA) patients failed to improve ankle symptoms and function when compared to placebo injections - yet another trial showing that intraarticular injections are seldom beneficial.

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Hip

Pfizer/Lilly Pull Tanezumab Development

Oct 26, 2021

Today, Lilly and Pfizer announced their global clinical development of the NGF inhibitor, tanezumab, has been discontinued due to recent negative opinions from the EMA and FDA advisory committee.



This decision mirrors that of other companies (AbbVie, AstraZeneca, Johnson & Johnson

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ICYMI: Propensity matched comparison of Tramadol vs Codeine use. Tramadol had a signif. higher risk of all-cause mortality (HR, 2.31), CV events (HR 1.15) & fractures (HR 1.50), but no diff in falls, delirium, constipation, opioid abuse, sleep disorders. https://t.co/nBUe5VV1D3 https://t.co/C3r0Fur4xJ
Dr. John Cush @RheumNow( View Tweet )
Oct 24, 2021
ICYMI:Pregabalin (lyrica) for Fibromyalgia 75 mg bid; may be increased to max dose 450 mg/d.(Reduce for renal dz). Indications: DM neuropathy/pain, post-herpetic neuralgia, partial seizures. Rare AE: Angioedema, low Plts, ^PR interval, rhabdo, gynecomastia https://t.co/r4cH7n9qWD

Dr. John Cush @RheumNow( View Tweet )

Oct 23, 2021
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RheumNow Podcast – Rheumatologist Smoke-Enders (10.22.2021)

Oct 22, 2021

Today I have a few questions: Is tramadol really a weak narcotic? Should we really still be doing placebo-controlled trials? What are we going to do about our patients who are smokers? This and more, in this week's review of the news and journal articles.

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