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Fibromyalgia/Pain

Fibromyalgia Therapies Show Limited Evidence of Pain and QOL Reduction

Oct 27, 2020

JAMA Internal Medicine has published a review showing that most currently approved therapies for fibromyalgia (FM) do not have high-quality evidence to support their use; with some reducing pain or improving quality of life (QOL) in the short term, but overall effect size is not impressive.

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IL-1 Inhibition Alters Arthroplasty Rates

Oct 07, 2020

A subanalysis of the CANTOS trial suggests that inhibition of interleukin-1β (IL-1β) can reduce rates of incident hip or knee replacement (THR/TKR) surgeries.

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RheumNow Podcast – Function Follows Form (10.2.20)

Oct 01, 2020

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com. Regulatory approvals, update on global rheumatology alliance, smoking and psoriasis, gabapentin let down and defining difficult RA.

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Gabapentin Fails to Lessen Chronic Pelvic Pain

Sep 27, 2020

Lancet reports that in a randomized, blinded, controlled trial, gabapentin failed to significantly lower pain scores in women with chronic pelvic pain, and was associated with higher adverse event rates compared to placebo.

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Global task force establishes protocols for medical cannabis use to treat pain. Start low (5mg CBD) and titrate up (max 40 mg) - ALL Expert opinion, no good evidence (largely bunk?) https://t.co/HyYU0tGVF5

Dr. John Cush RheumNow ( View Tweet)

Sep 23, 2020

Has the Risk of Hip Fracture Changed over Time?

Sep 16, 2020

Data from the Framingham Heart Study has shown that hip fracture incidence has decreased over time, probably resulting from improved lifestyle changes (less smoking and heavy drinking). 



The incidence of hip fracture has been shown to be decreasing in the US, presumeably attributeable

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NSAIDs Shows No Advantage over CBT in Knee Osteoarthritis

Sep 16, 2020

JAMA Internal Medicine reports on a controlled clinical trial of knee osteoarthritis patients wherein meloxicam responses were not significantly or clinically superior to placebo or CBT (after placebo).



Because of the uncertain benefits and safety of long-term NSAIDs,

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Sleep, Fatigue and Depression in Psoriatic Arthritis

Aug 28, 2020

Comorbidities are highly prevalent in psoriatic disease. A recent study in Arthritis Research & Therapy suggests a high prevalence of sleep disturbances, fatigue, and anxiety/depression in psoriatic arthritis (PsA) that is unrelated to skin disease musculoskeletal (MSK)

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EHR review of acute MSK injuries (13+ million participants) finds prolonged opioid use in high-risk pts (workers' comp, VA pts, substance abuse ) to be 27% but only 6% in low-risk pts; persistent opioid increased w/ older age and physical comorbidity https://t.co/y

Dr. John Cush RheumNow ( View Tweet)

Aug 28, 2020

RheumNow Podcast – Rheum Lives Matter (8.28.20)

Aug 28, 2020

Dr. Jack Cush reviews the news and journal articles from the past week. Of mice and men in cartilage, the efficacy of JAK inhibitors in patients who are having skin problems, nrAxSpa has its own diagnostic code, metformin, talking about Back Talk, plus so much more.

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Fibromyalgia & Exercise? Systematic review of 50 trials, shows that, compared to usual care, exercise had moderate effect on fatigue, small effect on sleep and meditative exercise programs were the most effective for improving sleep quality.

Dr. John Cush RheumNow ( View Tweet)

Aug 24, 2020
Telemedicine: What's Changed and What Needs to be Addressed? An update on legislative changes, uncertainties, and the care gap post COVID https://t.co/HRAsEP7IL6 https://t.co/X6PL0W4tI7
Dr. John Cush RheumNow ( View Tweet)
Aug 23, 2020

ACP/AAFP Guidelines on Managing Musculoskeletal Pain

Aug 17, 2020

Topical nonsteroidal anti-inflammatory drugs (NSAIDs) are recommended as first-line therapy in a new guideline for treating acute, non-low back pain from musculoskeletal injuries in outpatient settings.



The clinical guide, released by the American College of Physicians (ACP) and the

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Check out my Virtual Video Exam - 5 minutes of a combo of Simon Sez and the Macarena hits the high points of a functional virtual examination. https://t.co/iwHTJKQtEC

Dr. John Cush RheumNow ( View Tweet)

Aug 14, 2020

Rheumatic Diseases, Drugs and COVID-19 Guidelines

Aug 13, 2020

Several recent publications have focused on the risk and outcomes of rheumatic disease (RDD) and autoimmune patients who become infected with SARs-CoV-2.

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RheumNow Podcast - Why we Love Rheumatology Fellows (8.7.20) Watch it here>> https://t.co/ftrycqoWRR or Listen to the podcast on iTunes or on SoundCloud>> https://t.co/gi5hO0HaIl

Dr. John Cush RheumNow ( View Tweet)

Aug 09, 2020

RheumNow Podcast – Why Do We Love Rheumatology Fellows? (8.7.20)

Aug 06, 2020

Dr. Jack Cush reviews why we all love our rheumatology fellows and our best advice for them stemming from these articles.

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Full read clinical practice guideline on obesity management from the Canadian Medical Assn Journal. https://t.co/YdbjtnBcST

Dr. John Cush RheumNow ( View Tweet)

Aug 05, 2020
Virtual Video Joint Exam Pearl #1: pain elicited by cervical lateral bending (in someone w/ otherwise normal Cx ROM) is highly correlated with Tender trigger points in the neck region (hence #FM)

Dr. John Cush RheumNow ( View Tweet)

Aug 04, 2020

Uric Acid Targeting in Gout Management

Jul 31, 2020

A study from 2 gout clinics implementing different treatment strategies has shown that a treatment strategy that aims to strictly achieve low uric acid (UA) results in a higher a rate of targetd serum UA lowering and less gout flares.



Two gout clinics with 212 newly diagnosed gout

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FDA recommends health care professionals discuss naloxone with all patients when prescribing opioid pain relievers or medicines to treat opioid use disorder.

Dr. John Cush RheumNow ( View Tweet)

Jul 30, 2020
Metanalysis of 10 studies ( p534 patients) shows that exercise in ankylosing spondylitis improves pain, function and disease activity. Statistically signif improvement in pain (P<0.0001), BASDAI (P <0.00001), and BASFI (P<0.00001), but not CRP and ESR.

Dr. John Cush RheumNow ( View Tweet)

Jul 30, 2020
FDA has issued draft guidance on Cannibis research: “Cannabis & Cannabis-Derived Compounds: Quality Considerations for Clinical Research, Draft Guidance for Industry,” outlines FDA’s current thinking on clinical research related cannabis-derived compounds https:

Dr. John Cush RheumNow ( View Tweet)

Jul 23, 2020

Meloxicam Superior to Placebo and Cognitive Behavioral Therapy in Knee OA

Jul 20, 2020

Pain management in knee osteoarthritis (OA) is confounded by studies showing less is equal to usual standards of care. A recent trial showed that meloxicam was superior to placebo or cognitive behavioral therap (CBT); although the differences were small. 

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MMWR reports 2019 survey data showing 6.6% of women used opioid during pregnancy. 21% admitted misuse, 27% wanted to stop/reduce narcotic use and 32% did not receive MD counseling about how opioid use could affect an infant. https://t.co/Ybrjv4Anmk

Dr. John Cush RheumNow ( View Tweet)

Jul 17, 2020
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