RheumNow Podcast - Best of EULAR 2021
Jun 11, 2021
Dr. Jack Cush reviews and highlights his favorite abstracts and presentations from last week's virtual EULAR 2021 meeting.
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Popular article: Best Interventions for Gout Flares
https://t.co/duhEHJG9eY https://t.co/tJRwuMPhUR
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Dr. John Cush @RheumNow( View Tweet )
Jun 19, 2021
Ten Things to Tell Patients About Diet and Rheumatic Disease: Dr. Eric Dein ( @ejdein1 )
https://t.co/q2Mc1gLZig https://t.co/iV5JO8m5Sv
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Dr. John Cush @RheumNow( View Tweet )
Jun 16, 2021
Dr Dehlin presents Swedish data showing ⬆️ risk of all cause mortality (HR: 1.08 (95% CL: 1.05-1.11) and most comorbidities but a ⬇️ risk dementia in gout 0.68 (0.60-0.77) @RheumNow #EULAR2021 Abstr#OP0208 https://t.co/0ojpSbfIHM
Richard Conway @RichardPAConway( View Tweet )
Jun 04, 2021
My toe hurts & it’s a killer! Gout is related to ⬆️comorbidities - clusters incl no comorbidities to worse outcomes if CRF in gout. HTN⬆️ Gout has SNIPs assoc w HTN & May be the cause. Incident Gout assoc with Acute coronary syndrome OP0193 OP0192 #EULAR2021 @RheumNow @eular_org https://t.co/CS6o0T1FL2
Janet Pope @Janetbirdope( View Tweet )
Jun 04, 2021
Novartis announced that Cosentyx (secukinumab) has received FDA approval for treatment of children and adolescents with moderate to severe plaque psoriasis #EULAR2021 https://t.co/JlkmjLwqQ8
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Dr. John Cush @RheumNow( View Tweet )
Jun 02, 2021
Featured Abstracts from Industry at EULAR 2021
Jun 02, 2021
Many great presentations this week at EULAR 2021 will feature industry sponsored clinical trials and reports. Often these become the pivotal studies for regulatory approval and the annual congresses are their first look.
Below is a collection of the industry press releases detailing
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Best Interventions for Gout Flares
May 31, 2021
A recent metanalysis assessed the comparative efficacy of current first-line pharmacologic antiinflammatory interventions for gout flares and surmised that canakinumab and intravenous or intramuscular corticosteroids are superior to nonsteroidal antiinflammatory drugs [NSAIDs].
From
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Study of National inpatient sample database (2015 to 2017) showed the frequency of atrial fibrillation in rheumatic disease (RD) pts finding that AF frequency highest in gout followed by vasculitis, and PMR. RD Mortality was 2 fold higher with AF. https://t.co/enno6hrKOI
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Dr. John Cush @RheumNow( View Tweet )
May 31, 2021
COLCORONA: Protective Effect of Colchicine in COVID-19
May 31, 2021
Lancet Respiratory Medicine has reported the results of the COLCORONA trial, showing that in patients with PCR-confirmed COVID-19 infection, colchicine led to a significantly lower rate of death or hospital admission from COVID.
Colchicine is an oral anti-inflammatory agent with
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News: Factors Associated with COVID-19 Deaths in Rheumatic Patients
https://t.co/FzsINtpZEz https://t.co/QzuLZRKaZy
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Dr. John Cush @RheumNow( View Tweet )
May 25, 2021
RheumNow Podcast – Myth Busters (5.21.2021)
May 21, 2021
Dr Jack Cush reviews the news and journal reports from the past week on RheumNow.com
Metanalysis (11 RCTs, 19 registries) of Pulm arterial HTN assoc. w/ CTD (w/ 1,267 & 4,008 CTD-PAH pts), showed Investigational Rxs reduced morbidity/mortality by 36%. CTD-PAH survival
"Arthritis Mutilans" - worse outcome to chronic inflammatory arthritis is due to 5 disorders:
1) RA
2) Psoriatic arthritis
3) Tophaceous gout
4) polyarticular JIA
5) Multicentric reticulohistiocytosis (Ive never seen this!!)
https://t.co/XYmBEW1F0R https://t.co/tGWNG9Aklw
Dr. John Cush @RheumNow( View Tweet )
May 17, 2021
RheumNow Podcast – BandAids for Rheumatologists (5.14.2021)
May 14, 2021
Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com - a website for rheumatologists, by rheumatologists.
We love Rheumatology!
CDC study from 33 sites, 25 states showed vaccine efficacy (against Sx COVID) in HCP was 82% with ONEdose
RheumNow Live 2021 Now Available for All
May 14, 2021
RheumNow Live (RNL) for 2021 was held March 20 - 21 in Fort Worth, TX, and now all can partake in the meeting - by video, podcast or by signing up for Tuesday Nite Rheumatology (TNR).
RNL has finished its 3rd year as a hybrid meeting, with the live meeting streamed to hundreds at home
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A retrospective cohort study of 419 gout patients compared low dose 0.6 mg qd (LD) vs regular 0.6 mg bid (RD) colchicine as prophylaxis when starting urate lowering therapy. Rate of gout flares were roughly equal (LD 14.3% vs RD 11.3%) https://t.co/8G6siQlHbI
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Dr. John Cush @RheumNow( View Tweet )
May 11, 2021
RheumNow Podcast – Falling or Falling in Love?
May 06, 2021
Dr. Jack Cush reviews the best journal articles from the past week on RheumNow.com.
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News Feature: Uric Acid: A Major Player in the Metabolic Syndrome
Uric acid, and hyperuricemia, has been closely linked with may of the components of the metabolic syndrome, which is largely a consequence of excessive fat storage.
https://t.co/ObQ0LURodb https://t.co/HT35ODnFkn
Links:
Dr. John Cush @RheumNow( View Tweet )
May 04, 2021
Uric Acid: A Major Player in the Metabolic Syndrome
May 03, 2021
An open source, free read from the European Journal of Internal Medicine discusses how uric acid has evolved from the toxic cause of gout and nephrolithiasis and evolved, by way of science, into a pleiotropic recidivist in the evolution of obesity, diabetes, insulin resistance, renal disease,
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RheumNow Podcast is Up! – with news of Uppers and Downers. Read about Vaccine success, CKD gout prophylaxis, TOFA in AS & too much IL-17 inhib can be a problem https://t.co/kt63YrQ0Sw Listen iTunes> https://t.co/FHJv01AAbC or Android SoundCloud>>https://t.co/IyYvjkWUc1
Dr. John Cush @RheumNow( View Tweet )
Apr 30, 2021
RheumNow Podcast – Uppers and Downers
Apr 30, 2021
Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com.
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Gout Prophylaxis in patients with severe CKD? Metanalysis of 33 studies suggests 1) lack of good data guidance; 3) Colchicind is associated w/ toxicity w/ CKD (neuromyopathy, rhabdomyolysis; 3) anakinra - works, expensive, little/no toxicity https://t.co/VhI0wRC0VO
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Dr. John Cush @RheumNow( View Tweet )
Apr 29, 2021
RheumNow Podcast – Upadacitinib Wins in PsA (4.2.2021)
Apr 02, 2021
Dr Jack Cush reviews the news and Journal reports and takes "Back Talk" questions from viewers.
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Inflammatory Conditions Up the Risk of Premature Myocardial Infarction
Mar 31, 2021
The European Journal of Preventive Cardiology reports that younger patients with their first myocardial infarction before age 50 yrs have a higher risk of having a systemic inflammatory disease (SIDs) and higher rates all-cause mortality.
Data derived from the retrospective
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Metanalysis of 32 studies shows most forms of arthritis assoc w/ incr risk of CVA (ischemic stroke: RR=1.53 or hemorrhagic stroke: RR=1.45), esp for RA (RR=1.38), AS (RR=1.49), PsA (RR=1.33), gout (RR=1.4) --risk higher with age <45 years (RR=1.46) https://t.co/YDiebrqtbi
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Dr. John Cush @RheumNow( View Tweet )
Mar 31, 2021
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