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Gout

RheumNow Podcast – Pounds of Prevention (3.5.2021)

Mar 04, 2021

Dr. Jack Cush reviews and discusses nearly a dozen news reports and journal articles from the past week on RheumNow.com.

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Weight Loss to Avert Risk of Gout

Mar 03, 2021

Analysis of the NHANES population survey data shows weight gain during adulthood increases the risk of gout and that maintaining normal weight could reduce the overall gout risk by nearly 33%.



Obesity and gout have long been linked, but the the influence of weight changes during

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Combo Therapy Boosts Response in Uncontrolled Gout

MedPage Today
Mar 02, 2021

The addition of an immunomodulating agent to pegloticase (Krystexxa) among patients with uncontrolled gout significantly improved response rates, a systematic literature review found.



In a cohort of patients whose gout had been refractory to conventional therapy, co-treatment with

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We are three weeks out from RheumNow Live. Are you planning on attending? https://t.co/vJlU0Z3Q3x

Dr. John Cush @RheumNow( View Tweet )

Feb 26, 2021
News Feature: ANAGO Study - Anakinra for Gout Flare https://t.co/btP7ivMuPO https://t.co/HHsUKsjjuI
Dr. John Cush @RheumNow( View Tweet )
Feb 25, 2021

ANAGO Study - Anakinra for Gout Flare

MedPage Today
Feb 23, 2021

The interleukin (IL)-1 receptor antagonist anakinra (Kineret) was not superior to triamcinolone for relieving gout flares, but had similar effects for pain reduction as the glucocorticoid, a randomized phase II study found.

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SF analysis usually confirms dx, but changes dx 14%. 264 SF samples showed MSU crystals in 89% gout, 9% of CPPD pts. CPP crystals found in 54% of CPPD, 43% of OA & 7% of gout pts. Ca hydroxyapatite seen 1/3 RA, 1/2 OA & 2/3 CPPD https://t.co/B8UkHagXK3 https://t.co/UTncLo6Fyu
Dr. John Cush @RheumNow( View Tweet )
Feb 19, 2021
MIRROR Study: Pegloticase With Methotrexate in Uncontrolled Gout Botson et al has reported that the combination of methotrexate (MTX) and IV pegloticase is safe and effective in patients with uncontrolled gout. https://t.co/DRkIMOAhs4 https://t.co/2dft1QjC6E
Dr. John Cush @RheumNow( View Tweet )
Feb 17, 2021

MIRROR Study: Pegloticase With Methotrexate in Uncontrolled Gout

Feb 15, 2021

Botson et al has reported that the combination of methotrexate (MTX) and IV pegloticase is safe and effective in patients with uncontrolled gout.

This exploratory, open-label clinical trial screened 17 patients and treated 14 patients (all men, 49.3 ± 8.7 years) with IV pegloticase with MTX (15

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QD Clinic Podcast from Last week. iTunes https://t.co/FHJv01AAbC or SoundCloud https://t.co/dfSTkSbY2d QD Clinics (123-127; Feb 5) QD127 - Chronic Monarthritis QD126 - Fever by the Numbers QD125 - "What Were You Thinking" QD124 - No Win Consults QD123 - When RA Meets UC https://t.co/ReOFOVooje
Dr. John Cush @RheumNow( View Tweet )
Feb 08, 2021
UK Biobank examined the association between comorbidities & uric acid (SUA). Comorbidities assoc w/ increasing SUA. For each 1 mg increase in SUA, there is a 1-3 fold incr risk of HTN, IHD, CCF, ^HL, CKD https://t.co/ZEPAPRq62k

Dr. John Cush @RheumNow( View Tweet )

Feb 08, 2021
Consults in Cars--have telehealth consults gone too far? https://t.co/INbKZ3xxty https://t.co/X2RwktCd2U
Dr. John Cush @RheumNow( View Tweet )
Feb 03, 2021
Our Top January Tweet: Urate Lowering Therapy During Acute Gout Acute gout has its well-defined protocols, and most state that urate lowering therapy should be continued; but does ULT affect outcomes in an acute gout attack? https://t.co/aDHpU1qrlu https://t.co/6xDwyVjuyC
Dr. John Cush @RheumNow( View Tweet )
Feb 01, 2021
QD Clinic Podcast for the week of Jan 29 - Pearls from Practice This wk: Arthritis &Crohn's Rhabdo or Not Dadgummit, Where's Waldos COVID Vaccine? "I Don't Know" A Tale of Two Gouts https://t.co/7ndYSOgh5R or listen on iTunes https://t.co/FHJv01AAbC https://t.co/780P7Bdw8F
Dr. John Cush @RheumNow( View Tweet )
Jan 30, 2021

RheumNow Podcast – Rheumatology Burnout (1.29.2021)

Jan 28, 2021

Dr. Jack Cush reviews this past week's journal articles and news features on RheumNow.com. Colchicine, vaccine rollout, risk of RA in endometriosis patients, tREACH trial, lupus nephritis news, rheumatology burnout and more.

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Colchicine suppresses MSU & CA pyrophosphate crystal activation of Nod-Like Receptor Protein 3 (NLRP3) inflammasome, thereby suppressing caspase-1 activation and the subsequent release of IL-1β and IL-18. Great review by Pillinger et al https://t.co/n7MHtSviT5

Dr. John Cush @RheumNow( View Tweet )

Jan 28, 2021
Urate Lowering Therapy During Acute Gout Acute gout has its well-defined protocols, and most state that urate lowering therapy (ULT) should be continued; but does ULT affect outcomes in an acute gout attack? https://t.co/aDHpU1I2d2 https://t.co/QihJNhMW8L
Dr. John Cush @RheumNow( View Tweet )
Jan 28, 2021
Rheums: Got a Rheumatology question or case for RheumNow? Record it here and we'll feature it on an upcoming podcast. Tell us your name and where you practice rheumatology. https://t.co/wzNmOzH4VE https://t.co/6w8CAAUkO6
Dr. John Cush @RheumNow( View Tweet )
Jan 26, 2021

Urate Lowering Therapy During Acute Gout

Jan 26, 2021

Acute gout has its well defined protocols, and most state that urate lowering therapy (ULT) should be continued; but does ULT affect outcomes in an acute gout attack?

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Sign up to attend RheumNow Live--March 20 and 21. CME credits available https://t.co/vJlU0Z3Q3x https://t.co/Z0ectgFD2d
Dr. John Cush @RheumNow( View Tweet )
Jan 20, 2021
2020 Rheumatology Year in Review-- Read our top news items that rheumatologists should recollect and integrate into clinical standards for 2021 and beyond. https://t.co/QisCpdcLEa https://t.co/pZekUvcomE
Dr. John Cush @RheumNow( View Tweet )
Jan 16, 2021
Download your RheumaKnowledgy Card https://t.co/L7O0UFjEBV https://t.co/iFtVKERnjC
Dr. John Cush @RheumNow( View Tweet )
Jan 12, 2021
ACR Convergence 2020 Late Breaking Abstracts available from the ACR "Spotlight" slide give away. 10 slides on COVID, Tyk2 in PsA, FAST febuxostat study, Tofa in AS and novel drugs for SLE and PSS https://t.co/DvcDyusCUR

Dr. John Cush @RheumNow( View Tweet )

Jan 11, 2021
Rheumatologists: Record your question or case for the RheumNow podcast. https://t.co/NDhYNX50e2

Dr. John Cush @RheumNow( View Tweet )

Jan 09, 2021
Join us this March for RheumNow Live! Sign up via the link below. https://t.co/vJlU0Z3Q3x https://t.co/G1s3F7zKlI
Dr. John Cush @RheumNow( View Tweet )
Jan 05, 2021
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