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Pediatric Rheum

RheumNow Podcast – Falling or Falling in Love?

May 06, 2021

Dr. Jack Cush reviews the best journal articles from the past week on RheumNow.com.

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Childhood Lupus May Hamper Adult Careers

May 04, 2021

Long-term outcomes of kids with childhood-onset systemic lupus erythematosus (cSLE) are uncommon, but this cSLE cohort analysis suggests that SLE significantly impacts their future education, vocation, and employment as they reach adulthood.



A cohort of 106 cSLE (93% female, 73% White

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RheumNow Podcast – Uppers and Downers

Apr 30, 2021

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com.

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Psoriatic Pregnancies Pose Risks to the Mother, Not Child

Apr 27, 2021

A metanalysis of pregnancy outcomes in women with psoriasis and psoriatic arthritis finds an excess risk of adverse maternal events, but not adverse neonatal events.



This systematic review included 16 studies meeting inclusion criteria. 



Overall they found that pregnant women

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RheumNow Podcast – Coconspirators: RA and Lung Disease

Apr 23, 2021

Dr. Jack Cush reviews and discusses more than a dozen news and journal articles from the past week on RheumNow.com.

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Autoimmune Risk of Death Up during COVID

Apr 15, 2021

A population-based study in the UK shows that patients with rare autoimmune rheumatic diseases (RAIRD) were 44% more likely to die during the 2020 COVID-19 pandemic (March - April) compared to either the general population or their pre-COVID risk.



This cohort study compared hospital

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RheumNow Podcast – Upadacitinib Wins in PsA (4.2.2021)

Apr 02, 2021

Dr Jack Cush reviews the news and Journal reports and takes "Back Talk" questions from viewers.

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Hypertension Unaffected by Urate Lowering Therapy

Mar 30, 2021

Does uric acid contribute to the risk of hypertension (HTN)?  A recent cohort trial shows that allopurinol in young adults does not sufficiently lower blood pressure (BP).



Previous research in a small cohort of obese hypertensive kids showed that urate lowering therapy was assoaciated

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RheumNow Podcast – Great Associations (3.19.2021)

Mar 18, 2021

Dr. Jack Cush rants on the journal reports, news and FDA actions featured this past week on RheumNow.com.

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Apremilast Equals MTX in Palmoplantar Psoriasis

Mar 18, 2021

Palmoplantar psoriasis (PPP) is a therapeutically challenging variant of psoriasis; nonetheless, a prospective, randomized, active-controlled trial from India suggests that apremilast is effective and safe in patients with PPP.

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MDA-5 Antibodies and Juvenile Dermatomyositis

Mar 17, 2021

A multicentre, retrospective study examined MSA profiles (by immunoprecipitation) from 96 juvenile idiopathic inflammatory myopathies (JIIM) at nine pediatric rheumatology centres in Japan. MSA were found in 85 of 96 cases with over 90% of patients having one of the following three MSA types

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Analysis of 8416 pts w/ Kawasaki disease (KD) shows older and younger children differ. <10% were under 6 mos, 78%) were 6 mos-4yrs; 11% 5 to 9 yrs. Younger KD had more incomplete KD, coronary aneurysms, while older had more delayed diagnoses, more fever https://t.co/NkSmfg38ru

Dr. John Cush @RheumNow( View Tweet )

Mar 09, 2021

Higher Lupus Mortality Among Minority Populations

Feb 23, 2021

The February 19th MMWR reports that higher mortality rates in certain patients with systemic lupus erythematosus (SLE); data based on recent San Francisco County statistics showing a four fold higher mortality among Asian and Hispanic/Latina females with SLE.

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Very high levels of IL-18 IL-18 (> 10 000 pg/ml) is associated with Macrophage Activation syndrome (with systemic JIA) as well as primary and secondary Hemophagocytic lymphohistiocytosis (HLH) https://t.co/dotoaYbuPd

Dr. John Cush @RheumNow( View Tweet )

Feb 18, 2021
Common mucocutaneous findings in 35 kids w/ MIS-C & COVID: 1) conjunctival injection (21), palmoplantar erythema (18), lip hyperemia (17), periorbital erythema/edema (7), strawberry tongue (8), & malar erythema (6) https://t.co/mcSOXtXaEh

Dr. John Cush @RheumNow( View Tweet )

Feb 17, 2021
1975: Nixon & Bresnev, in effort of medical diplomacy, cooperated on JRA trials. (Fact: Stalin's personal physician was a rheumatologist.) Dr. Steven's shares an interesting historical slide about this collaboration. #RWCS2021 #RWCS @RWCSmtg @RheumNow https://t.co/Px71qfqDcy
Dr. Rachel Tate @uptoTate( View Tweet )
Feb 13, 2021
Some statistics regarding pediatric rheumatologists in the US and abroad. Here in the US we have under 30 fellowship options, 448 pediatric rheumatologists in 2019 (and growing), and patients/families are driving on ave 42.8 miles to get care. #RWCS2021 #RWCS @RheumNow @RWCSmtg https://t.co/RhTroEKcwN
Dr. Rachel Tate @uptoTate( View Tweet )
Feb 13, 2021
A serious shortage of pediatric rheumatologists in the USA, where we need at least 1 ped rheum per 400,000 population. @RWCSmtg https://t.co/o8XCkjUOaN
Dr. John Cush @RheumNow( View Tweet )
Feb 12, 2021
CARRA was established in 2000 to further pediatric Rheumatology through research and registries @RWCSmtg https://t.co/drXGz23QyN
Dr. John Cush @RheumNow( View Tweet )
Feb 12, 2021
Milestone achievements of the pediatric Rheumatology collaborative study group @RWCSmtg https://t.co/OGXd2YWj5A
Dr. John Cush @RheumNow( View Tweet )
Feb 12, 2021
Dr. Anne Stevens lecturing at @RWCSmtg on the history of pediatric Rheumatology. Sir Eric Bywaters was the Father of meeting day pediatric Rheumatology @RWCSmtg https://t.co/iZtPfgoyxa
Dr. John Cush @RheumNow( View Tweet )
Feb 12, 2021
Dr George F Still, among the first to write about children with arthritis, pediatric Rheumatology, in 1898, with his description of 22 kids with arthritis. @RWCSmtg https://t.co/Y6DOzooFjZ
Dr. John Cush @RheumNow( View Tweet )
Feb 12, 2021
Defects in NLRC4 inflammasome can drive IL 18 production in systemic JIA. @RWCSmtg https://t.co/ffzODTXd52
Dr. John Cush @RheumNow( View Tweet )
Feb 11, 2021
IVIg in MIS-C Among children with multisystem inflammatory syndrome (MIS-C), treatment with IVIG and methylprednisolone vs IVIG alone was associated with a more favorable fever course. https://t.co/iCyJd3bbao https://t.co/edgVLpMP5a
Dr. John Cush @RheumNow( View Tweet )
Feb 10, 2021

IVIg in MIS-C

Feb 08, 2021

Among children with multisystem inflammatory syndrome (MIS-C), treatment with IVIG and methylprednisolone vs IVIG alone was associated with a more favorable fever course. MIS-C is a rare but serious pediatric condition associated with COVID-19 where different body parts can become inflamed,

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