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Rheumatoid Arthritis

RheumNow Podcast – Pounds of Prevention (3.5.2021)

Mar 04, 2021

Dr. Jack Cush reviews and discusses nearly a dozen news reports and journal articles from the past week on RheumNow.com.

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Paucity of Effectiveness Research on Telemedicine in RA

Mar 02, 2021

A systematic review of telehealth in delivering equivalent care in RA patients demonstrates there is limited evidence that virtual RA care is equivalent to conventional face-to-face care. Despite current widespread use, there is a great need for credible well-designed research that will address

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Pooled analysis of 16 observational RA registries (27 583 patients) shows that seropositivity was associated with better remission, LDAS and withdrawal rates for RTX and ABA, but not TNF inhibitors. https://t.co/aNphJpB7JB

Dr. John Cush @RheumNow( View Tweet )

Mar 01, 2021
QD Clinic - RA or Not? Lessons from the clinic. Enough serology, but not enough joints - when does it become RA? https://t.co/akklOklPee

Dr. John Cush @RheumNow( View Tweet )

Feb 28, 2021
We are three weeks out from RheumNow Live. Are you planning on attending? https://t.co/vJlU0Z3Q3x

Dr. John Cush @RheumNow( View Tweet )

Feb 26, 2021
News Feature: Measurable Benefits withTreat-to-Target Management in RA https://t.co/iAvLWJGTXp https://t.co/XNtGhoWs5I
Dr. John Cush @RheumNow( View Tweet )
Feb 26, 2021
We are excited to share that Roy Fleischmann will be leading a discussion on future therapy in RA at RheumnNow Live next month. Sign up today to attend in person or virtually. https://t.co/vJlU0Z3Q3x https://t.co/uN1MrzWZA9
Dr. John Cush @RheumNow( View Tweet )
Feb 25, 2021

Measureable Benefits to Treat-to-Target Management in RA

Feb 24, 2021

Desai and colleagues have published that when a learning collaborative group focused on a treat‐to‐target approach was compared to usual care, a modest but significant impact on implementation, treatment changes and patient outcomes in RA patients managed with a treat‐to‐target approach was seen

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Cohort analysis of 12351 RA patients from CPRD registry - finds RA on both glucorticoids & PPI have a greater risk OP fractures (adj HR: 1.60, 95% CI: 1.35 to 1.89) vs non-use. Higher than the Fx Risk with either oral GC or PPI use alone (adj HR 1.2). https://t.co/oPMnJoHCjX https://t.co/eW7rpVeHa4
Dr. John Cush @RheumNow( View Tweet )
Feb 24, 2021
Retrospective cohort study shows the risk of RA was lower in T2DM/diabetes (aHR 0.73; 95% CI 0.67–0.79) vs without T2DM. This risk was lost in when statins were not used (aHR 0.89; 0.69–1.14). Statins (in T2DM) had a protective effect against RA onset https://t.co/CfMJIuGOXI

Dr. John Cush @RheumNow( View Tweet )

Feb 24, 2021
We are excited to announce that Jeff Sparks ( @jeffsparks) will be leading a discussion on ILD in RA at RheumNow Live this March. Register to attend today. https://t.co/uwxOVh142F https://t.co/bnittqkhKQ
Dr. John Cush @RheumNow( View Tweet )
Feb 23, 2021
QD Clinics- The Sawtooth Steroid Taper Sawtooth Steroid Taper Surgery Rules for DMARDs & Biologics RA & DVT Traveling to Medical Meetings during COVID Hemoptysis and SLE When to do Genetic Testing in Febrile Patients https://t.co/dZLqGUyizG https://t.co/PYsH7K6ByB
Dr. John Cush @RheumNow( View Tweet )
Feb 23, 2021
Analysis of incident #RA in UK Clinical Practice registry shows recent prednisone >=7.5mg/d is assoc w/ hypertension in RA. In 17760 RA pts, 42% were Rx steroids; recent GC yielded a 17% increase in HTN (HR 1.17); only >7.5mg/D implicated https://t.co/qUKs2oZZUV https://t.co/pWmD4nKs6U
Dr. John Cush @RheumNow( View Tweet )
Feb 22, 2021
QD Clinic - RA and DVT Counseling Patients on JAKs and Thrombotic Risk https://t.co/efQGtkrxHF https://t.co/mfhjZYMlUC
Dr. John Cush @RheumNow( View Tweet )
Feb 18, 2021
RWCS Highlights - Day 4 from Dr. Rachel Tate ( @uptotate) -Novel Therapies Year in Review (RA, SLE, OA) -Novel concepts in Pediatric Rheumatology -TeleRheumatology Update: Post-COVID, Pre-?? https://t.co/JoTV25suxD https://t.co/Id19zgRT37
Dr. John Cush @RheumNow( View Tweet )
Feb 17, 2021
30 #RA pts treated w/ tofacitinib x 12 mos w/ signif improvement in DAS28, CRP, & HAQ and attenuation of further bone loss, as measured by significantly increased osteocalcin, OPG, and vitamin D3, with decreased CTX levels correlating w/ DXA results https://t.co/RSXL38cJvs

Dr. John Cush @RheumNow( View Tweet )

Feb 16, 2021
🔥 Increased baseline prevalence and 40% higher risk of developing #Multimorbidity after #RA incidence/index vs general population @CrowsonCindy @JohnDavisIII #MayoClinicRheumatology ⁦@jrheum⁩ ⁦@NIAMSFunding⁩ ⁦@NIH⁩ https://t.co/8GolTowAGm

Elena MyasoedovaMD @MyasoedovaElena( View Tweet )

Feb 16, 2021
Prospective study of 162 early RA pts looked at Xrays (baseline & 5 yrs). RF & ESR predicted erosion & JSN progression; CCP predicted erosions; Smoking & high DAS28 > 5.1 predicted progression of erosions. Obesity negatively predicted JSN progression https://t.co/fue121hHVw

Dr. John Cush @RheumNow( View Tweet )

Feb 15, 2021

RWCS Highlights - Day 3

Feb 15, 2021

Day 3 report from the 2021 RWCS meeting in Maui (and virtually) includes pearls from the PsA 2020 Year in Review; fact vs. fiction on evidence based medicine: diet and rheumatic diseases; hot topics in allergy/immunology; and pediatric rheumatology highlights.

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Dr. Troum considers curcumin 500mg with black pepper BID for patients with inflammatory arthritis. Unclear if there is a relationship or need for monitoring for those with concomitant NSAIDs. #RWCS2021 #RWCS @RWCSmtg @RheumNow https://t.co/9sSWwWTtyv
Dr. Rachel Tate @uptoTate( View Tweet )
Feb 13, 2021
1975: Nixon & Bresnev, in effort of medical diplomacy, cooperated on JRA trials. (Fact: Stalin's personal physician was a rheumatologist.) Dr. Steven's shares an interesting historical slide about this collaboration. #RWCS2021 #RWCS @RWCSmtg @RheumNow https://t.co/Px71qfqDcy
Dr. Rachel Tate @uptoTate( View Tweet )
Feb 13, 2021

Weekly Semaglutide for Weight Loss in Adults

Feb 11, 2021

NEJM has reported the results of a trial showing semaglutide once weekly plus lifestyle intervention was associated with sustained, weight loss in overweight or obese adults; such that nearly one-third lost over 20% of their body weight.



Semaglutide, a once weekly glucagon-like

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309 RA pts from the Preconception Counseling in Active RA (PreCARA) cohort were treated according to a modified T2T approach, 188 children were born. 47% of pts were on a TNFi during Preg; 75% were in LDAremission before PREG but 90% by 3rd trimester https://t.co/eLffxrH0UV

Dr. John Cush @RheumNow( View Tweet )

Feb 11, 2021
Synovial Tissue Signature Guiding Targeted IL-6 Therapy in RA RNA sequencing-based stratification of rheumatoid arthritis synovial tissue showed stronger associations with clinical responses compared with histopathological classification. https://t.co/VZJuoZ3b5a https://t.co/QxDlnrrywE
Dr. John Cush @RheumNow( View Tweet )
Feb 11, 2021

ACR Promotes New COVID-19 Vaccine Clinical Guidance for Rheumatic Patients

Feb 10, 2021

The American College of Rheumatology has published a draft guidance on the use of COVID-19 vaccination in rheumatic disease and musculoskeletal disease patients, based on the efforts of the North American Task force. The document provides guidance to rheumatology providers on the use of the

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