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Herpes Zoster Vaccine Update

Shingrix (GSK), the herpes zoster subunit vaccine (a two-shot series), was approved by the FDA in Fall 2018 and is currently approved for use in adults 50 years and older.

ACR 2019 - Report from Day One (Sunday)

Sunday was the first full day of scientific sessions at the 2019 ACR/ARP meeting in Atlanta. Yesterday we shared our initial news articles, videos and more with you. Following is my roundup of day one. 

Delays in Diagnosis

A Focus on WOCBA (Women of Childbearing Age)

Many rheumatic diseases affect women of childbearing age. In the age of biologic therapy, women are achieving better disease activity and there are increasing numbers of women with rheumatic diseases attempting pregnancy. 

ACR 2018 - Day 3 Report

Highlights from Tuesday, day 3 of the ACR Annual meeting in Chicago, included:

The PEXIVAS Study –  2x2 Trial of Plasma Exchange and Reduced Steroids in ANCA-Associated Vasculitis (AAV) - Abstract #2788

Tweets

Jonathan Hausmann MD hausmannMD

7 months 3 weeks ago

Holy Molly! TNFi (etanercept, adalimumab, infliximab, or golimumab) completely prevented stokes in patients with DADA2. #ACR19 @RheumNow

Janet Pope Janetbirdope

7 months 3 weeks ago

Infections In out patients are increased as measured by antimicromial scripts with RA and TNFi use comparing popn controls and pre and post RA TNFi use in pan Iceland registry #ACR19 #ACR @RheumNow abstr 2873. Higher than controls pre &even more after TNFi https://t.co/SlkIPP9WsJ

Dr. Rachel Tate uptoTate

7 months 3 weeks ago

Icelandic study shows RA pts use more antimicrobials in the 2 yrs prior to TNFi tx and have increased use 2 yrs after tx. https://t.co/GyUdQT2NvD abs#2873 #ACR19 @RheumNow https://t.co/HKU2IOPwcw

Kanika Monga, MD DrKanikaMonga

7 months 3 weeks ago

- Risk of bDMARD withdrawal higher for TNFi monotherapy compared w/ cs/bDMARD combination - If monotherapy necessary, etanercept should be preferred over infliximab and adalimumab Silvagni E et al. BMJ Open 2018 #ACR19 @RheumNow

Maeve Gamble MaeveGamble

7 months 3 weeks ago

Abstr#2273: higher placental transfer antiTNFs=ADA,IFX,GOL. Less transfer=CTZ,ETN. No ⬆️ in infxns in offspring, even with 3rd tri exposure. Potential trend for ⬆️ in serious infxns (>/=1 hosp adm 1st yr of life) with high placental transfer antiTNFs, not sig.

Dr. Antoni Chan synovialjoints

7 months 3 weeks ago

5-year effectiveness of TNFi in patients with early axSpA shown, male gender, HLAB27 positive and presence of at least one objective sign of inflammation or structural damage are more frequently associated with effectiveness #2776 by Molto #ACR19 @RheumNow

k dao KDAO2011

7 months 3 weeks ago

#acrbest @rheumnow #acr19 abstr#1901 VERY IMPT STUDY: 16,490 offspring of moms w/Rheum Dz: 105 on nonTNFi biologic or TOFA: NO ⬆️in utero SIE . Only 2 cases of SIE- 1 w/TOFA &1 w/ABT. Risk for SIE in utero For healthy 1.6% For TNFi 2.3% For nonTNFi + TOFA 2.1%

Dr. Antoni Chan synovialjoints

7 months 4 weeks ago

Does anti-TNF treatment halt radiographc progression in ankylosing spondylitis? #ACR19 @RheumNow Vote here 👇

Olga Petryna DrPetryna

7 months 4 weeks ago

Do you routinely use TNF inhibitors in your autoimmune patients with preexisting CHF?

Dr. Antoni Chan synovialjoints

7 months 4 weeks ago

2 papers looking at TNFi on radiographic progression in Ankylosing Spondylitis. TNF inhibitor treatment slowed radiologic progression when compared to other therapies but covariables such as smoking and NSAIDs need to be considered #ACR19 @RheumNow

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